Genetic analysis of an ambler class A extended-spectrum beta-lactamase from Capnocytophaga ochracea.
نویسندگان
چکیده
A beta-lactamase gene (cfxA3, 966 bp) was isolated from a beta-lactam-resistant Capnocytophaga ochracea clinical isolate and amplified using primers from the cfxA gene of Bacteroides vulgatus. The MICs of third-generation cephalosporins were much higher than those of the transconjugant Escherichia coli strain. The deduced protein sequence, by comparison with CfxA2 of Prevotella intermedia, had a Y239D substitution and possessed the characteristics of a class A, group 2e beta-lactamase.
منابع مشابه
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 42 2 شماره
صفحات -
تاریخ انتشار 2004